[18F]FMISO radiotracer produced as single dose equivalent to those manufactured in bulk

The use of PET and combined modalities PET/CT or PET/MRI have dramatically improved the standard of care for patients in the last thirty years. However, access to radiotracers is far from trivial. The average cost for equipment, facilities and trained personnel can be close to 10 million USD, thus developing a centralized market model where the radiotracers are manufactured in bulk and then individual doses are shipped to hospitals or imaging facilities. An important caveat is that the doses can only reach a radius of ca. 3 hours in the best case, for fluorine-18 radiotracers. This manufacturing model hinders the application of PET to millions of patients that are outside the radius of central manufacturing sites. Read more.