Better imaging method for Ewing sarcoma response assessment

Functional imaging using FDG-positron emission tomography (FDG-PET) was able to predict response to treatment in Ewing sarcoma patients, and was superior to other anatomic imaging criteria, according to a new retrospective analysis.

The criteria used to determine disease progression are not fully standardized, with differing volume increases used by WHO, SWOG, and RECIST; response criteria, however, are consistent across definitions. “A new methodology for estimation of change in volume throughout treatment could generate more accurate and objective criteria for the definition of progression and response,” wrote study authors led by Laurence H. Baker, DO, of the University of Michigan Medical School in Ann Arbor. Read more.