SNAP won’t become Alzheimer’s

People with suspected non-Alzheimer pathophysiology (SNAP) probably aren’t going to progress to Alzheimer’s disease, two studies found.

In a longitudinal study from the Knight Alzheimer Disease Research Center at Washington University in St. Louis, the same low proportion (14% to 17%) of those with SNAP and those with no pathology at baseline went on to have amyloid accumulation in their brains, according to Brian Gordon, PhD, and colleagues.

In other data from the Harvard Aging Brain Study, people with SNAP didn’t have greater levels of tau in Alzheimer’s brain regions than those without any pathology, according to Elizabeth Mormino, PhD, and colleagues. Read more.