Patients with psoriasis associated with increased systemic arterial and subcutaneous adipose inflammation

Psoriasis is a chronic, inflammatory skin disorder associated with an increased risk for coronary artery disease, likely resulting from a systemic pro-inflammatory state. In addition, previous studies demonstrate that subcutaneous adipose tissue inflammation, which may contribute to the pathogenesis of psoriasis, is also associated with an increased risk of cardiovascular disease. Given the multiple associations demonstrated between psoriasis, inflammation, and atherosclerotic disease, the objective of this study was to assess the relationship between global vascular inflammation and subcutaneous adipose tissue inflammation in patients with moderate-to-severe psoriasis. Read more.