Poor Sleep Tied to Alzheimer-Related Pathology

Sleep health may be target for early intervention

Self-reported poor sleep was associated with a greater presence of several cerebrospinal fluid (CSF) biomarkers of Alzheimer’s disease, according to a cross-sectional study.

Disrupted sleep or lack of sleep has previously been linked to a greater risk for brain amyloid plaque on PET imaging, but the study is among the first to show an association between poor sleep and amyloid and other biological markers for Alzheimer’s disease in the spinal fluid, wrote Barbara Bendlin, PhD, of the University of Wisconsin-Madison, and colleagues. Read more.