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How prostate cancer cells mimic bone when they metastasize

Understanding this process could lead to innovative and improved therapies

Prostate cancer often becomes lethal as it spreads to the bones, and the process behind this deadly feature could potentially be turned against it as a target for bone-targeting radiation and potential new therapies. Read more.

How to make an open-source, computerized map of the brain

In search of a way to improve how scientists analyze brain images, researchers at the University of Wisconsin–Madison Waisman Center decided to build a brain.

Or at least, a brain model.

Waisman Center senior scientist Alexander Converse and colleagues from several international universities recently published a rhesus macaque brain atlas aligned to a magnetic resonance imaging (MRI) template. The result is a three-dimensional, computerized map of the rhesus brain. Read more.

Healing kidneys with nanotechnology

Each year, there are some 13.3 million new cases of acute kidney injury (AKI), a serious affliction. Formerly known as acute renal failure, the ailment produces a rapid buildup of nitrogenous wastes and decreases urine output, usually within hours or days of disease onset. Severe complications often ensue.

AKI is responsible for 1.7 million deaths annually. Protecting healthy kidneys from harm and treating those already injured remains a significant challenge for modern medicine. Read more.

Functional Imaging in Movement Disorders: Diagnostic Advantages

Parkinson disease (PD) affects an estimated 10 million people worldwide, surpassed only by Alzheimer disease.  Despite its prevalence, clinical diagnosis is rarely clear. Fortunately, functional imaging can help neurologists navigate diagnosis and inform treatment and patient outcomes. Read more.

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