Inflammation of heart muscle in sarcoidosis negatively affects coronary circulation

Inflammation of the heart muscle caused by sarcoidosis is associated with abnormal circulation in the arteries surrounding and supplying blood to the heart, according to a study published in the Journal of the American College of Cardiology: Cardiovascular Imaging.

The study, “Myocardial Blood Flow and Inflammatory Cardiac Sarcoidosis,” shows the direct negative effect of inflammation on coronary circulation in sarcoidosis patients, and underscores the fact that drugs that suppress the immune system and reduce inflammation of the heart muscle increase the widening capacity of the blood vessels of the heart. Read more.

18F-FDG-PET/CT vs CT in cancer detection

Imaging with 18F-FDG-PET/CT compared to CT for detecting cancer in patients with nonspecific signs and symptoms of cancer (NSSC) provides a higher diagnostic specificity and accuracy than does CT alone, according to a study published in The Journal of Nuclear Medicine.

Researchers from Denmark conducted a randomized prospective trial of patients with serious NSSC symptoms to determine if 18F-FDG-PET/CT was superior to CT as initial imaging modality in this patient group. Read more.

Imaging the birth of new brain cells

The adult brain was long regarded as being unable to grow new neurons—you were stuck with what you had. We know now that this view is wrong and that the human brain continues to produce new neurons throughout our lives. Read more.

PET imaging serotonin biomarker may predict suicide risk

According to statistics from the Centers for Disease Control, a suicide occurs every 13 minutes in the US. While there were more than 41,000 known suicides in 2013, an additional 1.3 million adults had attempted suicide in the previous year, and 2.7 million people made a plan to do so. There is a clear need for methods to help identify individuals at risk of suicide, and certain biomarkers could aid in such efforts. Using positron emission tomography (PET) imaging, a study has explored whether serotonin binding potential predicts future suicide attempts and ideation, as well as intent and lethality of suicidal behavior. Read more.

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