NITTP
Product No.:NTTP-95
CAS No.:150196-34-2

NTTP-97l
   
Product Name: NITTP
Synonyms:  1-(2-Nitro-1-imidazolyl)-2-O-tetrahydropyranyl-3-O- toluenesulfonyl-propanediol; 3-(2-Nitroimidazol-1-yl)-2-O-tetrahydropyranyl-1-O- toluenesulfonylpropanediol; NTTP
CAS No.:  150196-34-2
Molecular Formula:  C18H23N3O7S
Molecular Weight:  425.46
Application:  Precursor for [18F]FMISO([18F]Fluoromisonidazole)
Presentation:  Packaged in amber vials or amber screw-cap vials with teflon-coated stoppers under argon atmosphere

Storage and Stability

  • Store the product at -20 ºC, protected from light.
  • Short-term storage at higher temperatures does not affect product quality.

Notes

  • Complete documentation - Certificates of Analysis including testing reports of 1H-NMR and HPLC spectra for each shipment
  • Customized dispensing available

Research

  • Oh S.J. et al. Fully automated synthesis of [18F]fluoromisonidazole using a conventional [18F]FDG module. Nucl. Med. Biol. 2005, 32, 899-905.
  • Alauddin M.M. et al. Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model. Mol. Imaging 2004, 3, 76-84.
  • Lim J. et al. An efficient radiosynthesis of [18F]Fluoromisonidazole. Appl. Radiat. Isot. 1993,44,1085-1091.
  • Martin G.V. et al. Noninvasive detection of hypoxic myocardium using (18F( Fluoromisonidazole and positron emission tomography. J. Nucl. Med. 1992, 33, 2202-2208.
  • Rasey J.S. et al. Radiolabeled fluoromisoindazole as an imaging agent for tumor hypoxia. Int. J. Radiat. Oncol. Biol. Phys. 1989, 17, 985-991.

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