FMAU
Product No.：FMAU-95
CAS No.：69256-17-3
 |
|
| Product Name: | FMAU |
| Synonyms: | 2,4-(1H,3H)-Pyrimidinedione, 1-[2-deoxy-2-fluoro-beta-D- arabinofuranosyl]-5-methyl-; 1-(2-Fluoro-2-deoxy-beta-D-arabinofuranosyl)thymine; 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinesione; 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyluracil; 2’-Fluoro-5-methyl-arabinosyluracil; 2’-Fluoro-5-methyl-beta-D-arabinofuranosyluracil; 1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 5-Methyl-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2- yl]pyrimidine-2,4-dione; 5-Methyl-1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)uracil; 1-(2- Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; FMAU; beta-FMAU; beta-D-FMAU |
| CAS No.: | 69256-17-3 |
| Molecular Formula: | C10H13FN2O5 |
| Molecular Weight: | 260.22 |
| Application: | Reference standard for [18F]FMAU and [11C]FMAU (2’-deoxy-2’-[18F]fluoro-5-methyl-1-beta-D-arabinofuranosyluracil) |
| Presentation: | Packaged in amber vials or amber screw-cap vials with teflon-coated stoppers under argon atmosphere |
Storage and Stability
- Store the product at -20 ℃, protected from light.
- Short-term storage at higher temperatures does not affect product quality.
Notes
- Complete documentation - Certificates of Analysis including testing reports of 1H-NMR and HPLC spectra for each shipment.
- Customized dispensing available
Research
- Mangner T.J. et al. Synthesis of 2’-deoxy-2’-[18F]fluoro-beta-D-arabinofuranosyl nucleosides, [18F]FAU, [18F]FMAU, [18F]FBAU, [18F]FIAU, as potential PET agents for imaging cellular proliferation. Nucl. Med. Biol. 2003, 30,215-224.
- Alauddin M.M. et al. Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model. Mol. Imaging 2004, 3, 76-84.
- Alauddin M.M. et al. Synthesis and evaluation of 2’-deoxy-2’-18F-fluoro-5-fluoro-1-beta-D-arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression. J. Nucl. Med. 2004, 45, 2063-2069.