5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine (50 mg)
Precursor 2 for [18F]FMAU
5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine
Product No.:MAU-95
CAS No.:7288-28-0
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Product Name: |
5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine |
Synonyms: |
Pyrimidine, 5-methyl-2,4-bis[(trimethylsilyl)oxy]-; 2,4-Bis(trimethylsiloxy)-5-methylpyrimidine; 2,4-Bis(trimethylsilyl)-5-methyluracil; 2,4-Bis-O-(trimethylsilyl)thymine |
CAS No.: |
7288-28-0 |
Molecular Formula: |
C11H22N2O2Si2 |
Molecular Weight: |
270.48 |
Application: |
Precursor 2 for [18F]FMAU |
Presentation: |
Very sensitive to moisture; packed in dark glass crimp cap vials under argon atmosphere |
Storage and Stability
- Stored under argon in a desiccators; appears to be stable for months.
- Short-term storage at higher temperatures does not affect product quality.
Notes
- Complete documentation - Certificates of Analysis including testing reports of 1H-NMR and GC spectra for each shipment.
- Customized dispensing available
Research
- Mangner T.J. et al. Synthesis of 2'-deoxy-2'-[18F]fluoro-beta-D-arabinofuranosyl nucleosides, [18F]FAU, [18F]FMAU, [18F]FBAU, [18F]FIAU, as potential PET agents for imaging cellular proliferation. Nucl. Med. Biol. 2003,30, 215-224.
- Buursma A.R. et al. 18F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: invitro comparison with other PET tracers. Nucl. Med. Commun. 2006, 27, 25-30.
- Alauddin M.M. et al. Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model. Mol. Imaging 2004, 3, 76-84.
- Alauddin M.M. et al. Synthesis and evaluation of 2'-deoxy-2'-18F-fluoro-5-fluoro-1-beta-D-arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression. J. Nucl. Med. 2004, 45, 2063-2069