Desmethylflumazenil (50 mg)

Precursor for [18F]Flumazenil
Precursor for [11C]Flumazenil
Product No.: DFBE-95-0050

Desmethylflumazenil
Product No.:DFBE-95
CAS No.:79089-72-8


   
Product Name: Desmethylflumazenil
Synonyms: 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-fluoro-5,6-dihydro-6-oxo-,ethyl ester, 8-Fluoro-5,6-dihydro-6-oxo- 4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester; Desmethylflumazenil; Desmethyl-FMZ; Ro 15-5528
CAS No.: 79089-72-8
Molecular Formula: C14H12FN3O3
Molecular Weight: 289.26
Application: Precursor for [11C]Flumazenil / Precursor for 5-[18F]Flumazenil ([18F]FEF)
Presentation: Packaged in amber vials or amber screw-cap vials with teflon-coated stoppers under argon atmosphere

Storage and Stability

  • Store the product at -20 ℃, protected from light.
  • Short-term storage at higher temperatures does not affect product quality.

Notes

  • Complete documentation - Certificates of Analysis including testing reports of 1H-NMR and HPLC spectra for each shipment
  • Customized dispensing available

Research

  • Nagren K. et al. Methylation of amide and thiol functions with [11C]methyl triflate, as exemplified by [11C]NMSP, [11C]flumazenil and [11C]methionine. J. Labelled Compd. Radiopharm. 1998, 41, 831-841.
  • Maziere M. et al. Synthesis of Ethyl-8-fluoro-5,6-dihydro-5-[11C]methyl-6-oxo-4H- imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate (RO 15.1788-11C): A Specific Radioligand for the In Vivo Study of Central Benzodiazepine Receptors by Positron Emission Tomography. Int. J. Appl. Radiat. Isot. 1984, 35, 973-976.