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INSIDE in-beam PET monitors proton range

Hadron therapy is an advanced cancer treatment that employs beams of protons or carbon ions to deliver dose with sub-millimetre accuracy. The extreme precision of this approach, however, means that treatment can be compromised if the range of the charged particles differs from the treatment plan. As such, range verification techniques are under investigation, with PET imaging of positron emitters generated by the treatment beam already in clinical use. Read more.

Technique reveals movements of immune cells as they hunt for tumors

A study led by researchers at the Stanford University School of Medicine has for the first time demonstrated a way to visualize and monitor the behavior of immune cells used to treat cancer patients. The new technique allows researchers to see where immunotherapy cells go as they hunt down tumors in the human body. The imaging technique also reveals whether the immune cells, called T cells, have found a tumor; how many T cells have arrived at the tumor; and whether the T cells are alive. Read more.

Predicting mesothelioma prognosis with PET/CT

There is new evidence that the rate at which mesothelioma tumors metabolize glucose could provide significant prognostic information for mesothelioma patients and their doctors.

Pleural mesothelioma is an especially fast-growing asbestos-linked malignancy. It typically carries a grim prognosis but several factors can impact mesothelioma survival, including tumor characteristics that can only be measured using advanced PET/CT imaging. Now, researchers in Japan say one of those characteristics, known as total lesion glycolysis (TLG), is especially valuable for determining mesothelioma prognosis. Read more.

FDG-PET imaging reveals brain region that links stress and heart disease

In new research led by Massachusetts General Hospital and Mount Sinai, PET/CT imaging revealed that activity in a stress-sensitive structure within the brain is linked to risk of cardiovascular disease. 

Although the connection between stress and heart disease has been known for some time because of animal studies, the mechanism behind it wasn’t clear. This is the first time the region of the brain that connects stress to the risk of heart attack and stroke has been identified in animal models and humans. Read more.

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