S-(-)-IBZM (2 mg)

Precursor for S-(-)-[123/125I]IBZM
Reference standard for S-(-)-[*I]IBZM
Product No.: IBZM-95-0002

S-(-)-IBZM
Product No.: IBZM-95
CAS No.: 84226-06-2


   
Product Name:  S-(-)-IBZM
Synonyms:  Iodobenzamide, (S)-(-)-3-Iodo-2-hydroxy-6-methoxy-N[(1-ethyl-2-pyrrolidinyl)methyl]benzamide; Benzamide, N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-3-iodo-6-methoxy-
CAS No.:  84226-06-2
Molecular Formula:  C15H21N2O3
Molecular Weight:  404.24
Application:  Precursor for S-(-)-[123/125I]IBZM / Reference standard for S-(-)-[*I]IBZM
Presentation:  Packaged in amber vials or amber screw-cap vials with teflon-coated stoppers under argon atmosphere

Storage and Stability

  • Store the product at -20 ℃, protected from light.
  • Short-term storage at higher temperatures does not affect product quality.

Notes

  • Complete documentation - Certificates of Analysis including testing reports of 1H-NMR and HPLC spectra for each shipment
  • Customized dispensing available

Research

  • Kung H.F. et al. Dopamine D-2 receptor Imaging Radiopharmaceuticals: Synthesis, Radiolabeling and in Vitro binding of R(+)- and S(-)-3-iodo-2-hydroxy-6-methoxy- N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide. J. Med. Chem. 1988, 31, 1039-1043.
  • Cordes et al., Initial experience with SPECT examinations using [123I]IBZM as a D2-dopamine receptor antagonist in Parkinson’s disease Eur. J. Radiol. 1991, 12, 182.
  • Innis R.B. et al. Amphetamine-stimulated dopamine release competes in vivo for [123I]IBZM binding to the D2 receptor in nonhuman primates. Synapse 1992, 10, 177.
  • Ichise M. et al. Iodine-123-IBZM dopamine D2 receptor and technetium-99m-HMPAO brain perfusion SPECT in the evaluation of patients with and subjects at risk for Huntington’s disease J. Nucl. Med. 1993, 34, 1274.